Transcript expression of BMP signaling pathway members. The diagram indicates cellular locations of differentially expressed genes in the BMP signaling pathway in prostate stromal cells. Decorin, a negative regulator of TGFβ signaling, is produced by stromal cells, which may result in autocrine regulation of the pathway. BMP4 and BMP5 are produced by stromal cells and may be responsible for paracrine regulation of Inhibitor of Differentiation (ID) gene expression in the prostate.
Oudes et al. BMC Genomics 2006 7:92 doi:10.1186/1471-2164-7-92