Table 1

Relation between RSCU' and measures of expression for all codons of amino acids of degeneracy greater than one. For each codon, only the genes in which the corresponding amino acid has a frequency of at least 10 were considered. Major codons are underlined. w indicates G/U wobble (by Lander et al. 2001). * indicates translationally weak codons. The (+) sign indicates that the average RSCU' in class of 25% lowly expressed genes is significantly lower than the average RSCU' in class of 25% highly expressed genes, while the (-) sign represents the opposite. N.S. indicates that the RSCU' is not significantly different
A
 B
 C
 D
 E
Amino acid
 Codon
 tRNA GCN
 RSCU vs maximum expression
 RSCU vs breadth of expression
Ala
 GCA
 9
 N.S.
 +

GCCW
 0
 N.S.
 -

GCG*
 5
 -
 -

GCT
 29
 +
 +
Arg2
 AGA
 6
 N.S.
 +

AGG
 5
 -
 -
Arg4
 CGA
 6
 N.S.
 +

CGCW
 0
 N.S.
 -

CGG
 5
 N.S.
 N.S.

CGT
 7
 N.S.
 N.S.
Asn
 AAC
 28
 N.S.
 -

AATW
 1
 N.S.
 N.S.
Asp
 GAC
 18
 -
 -

GATW
 0
 +
 +
Cys
 TGC
 30
 N.S.
 N.S.

TGTW
 0
 N.S.
 N.S.
Gln
 CAA*
 11
 -
 -

CAG
 21
 +
 +
Glu
 GAA
 12
 N.S.
 +

GAG
 13
 N.S.
 -
Gly
 GGA
 9
 N.S.
 +

GGC
 15
 +
 N.S.

GGG*
 7
 -
 -

GGTW
 0
 +
 +
His
 CAC
 11
 N.S.
 N.S.

CATW
 0
 N.S.
 N.S.
Ile
 ATA*
 5
 -
 -

ATCW
 5
 +
 N.S.

ATT
 14
 N.S.
 +
Leu2
 TTA
 7
 -
 N.S.

TTG
 6
 N.S.
 N.S.
Leu4
 CTA*
 3
 -
 N.S.

CTCW
 0
 -
 -

CTG
 10
 +
 N.S.

CTT
 12
 -
 N.S.
Lys
 AAA
 17
 -
 N.S.

AAG
 17
 N.S.
 N.S.
Phe
 TTC
 12
 N.S.
 N.S.

TTTW
 0
 N.S.
 +
Pro
 CCA
 7
 +
 +

CCCW
 0
 -
 -

CCG*
 4
 -
 -

CCT
 10
 N.S.
 +
Ser2
 AGC
 8
 N.S.
 N.S.

AGTW
 0
 N.S.
 +
Ser4
 TCA
 5
 N.S.
 +

TCCW
 0
 -
 -

TCG*
 4
 -
 -

TCT
 11
 +
 +
Thr
 ACA
 8
 N.S.
 +

ACCW
 0
 N.S.
 -

ACG*
 6
 -
 -

ACT
 10
 N.S.
 N.S.
Tyr
 TAC
 14
 N.S.
 -

TATW
 1
 N.S.
 +
Val
 GTA*
 5
 N.S.
 +

GTCW
 0
 N.S.
 N.S.

GTG
 16
 -
 -

GTT
 11
 N.S.
 +

Kotlar and Lavner BMC Genomics 2006 7:67   doi:10.1186/1471-2164-7-67