Research article
The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA
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* Corresponding author: Peter C Dedon pcdedon@mit.edu
- † Equal contributors
1 Department of Biological Engineering, Massachusetts Institute of Technology, NE47-277, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
2 Center for Environmental Health Sciences, Massachusetts Institute of Technology, 56-235, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
3 Novartis Institute for Biomedical Research, 250 Massachusetts Ave., 3C-141, Cambridge, MA 02139, USA
4 University of Albany, Gen*NY*Sis Center, Room 211, 1 Discovery Drive, Rensselear, NY 12144-3456, USA
BMC Genomics 2006, 7:313 doi:10.1186/1471-2164-7-313
Published: 12 December 2006Additional files
Additional File 1:
Differential enrichment of GO categories identified in the comparison of yeast responses to enediynes and γ-radiation. The table lists the gene ontology categories identified as significantly enriched within the four sectors identified in the comparison of the enediynes response to that of γ-radiation.
Format: PDF Size: 57KB Download file
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Additional File 2:
GO categories identified as associated with single-strand or double-strand damage. The table is a list of the gene ontology categories enriched in the gene sets that were identified as associated with single-strand or double-strand damage.
Format: PDF Size: 48KB Download file
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Additional File 3:
Cytotoxicity dose-response curves for S. cerevisiae strain DBY747 treated with enediynes. The figure plots the cytotoxicity dose-response curve for exposure of strain DBY747 to enediynes.
Format: PDF Size: 157KB Download file
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Additional File 4:
Cytotoxicity dose-response curves for S. cerevisiae strain BY4741 treated with enediynes. The figure plots the cytotoxicity dose-response curve for exposure of strain BY4741 to enediynes.
Format: PDF Size: 125KB Download file
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