|
Comparison of evolutionary rate among three groups of genes |
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| UEHGs |
Disease genes |
Other genes |
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|
|
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| Mean(SEM) |
Median |
Range |
Mean(SEM) |
Median |
Range |
Mean(SEM) |
Median |
Range |
|
|
|
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| Ka |
0.053 (0.0015) |
0.033 |
0–0.48 |
0.080 (0.0017) |
0.061 |
0–0.70 |
0.092 (8.0E-4) |
0.066 |
0–1.37 |
| Ks |
0.58 (0.0047) |
0.57 |
0.076–2.0 |
0.63 (0.0043) |
0.61 |
0.14–2.4 |
0.66 (0.0022) |
0.62 |
0.041–4.2 |
| Ka/Ks |
0.088 (0.0023) |
0.059 |
0–0.59 |
0.12 (0.0023) |
0.10 |
0–0.70 |
0.13 (0.001) |
0.11 |
0–1.2 |
|
Ka, the number of non-synonymous substitutions per non-synonymous sites. Ks, the number of synonymous substitutions per synonymous site. Ka and Ks values are calculated based on human-mouse orthologous pairs as described in the main text. The first column in each group is the mean followed by standard error of the mean (SEM). | |||||||||
Tu et al. BMC Genomics 2006 7:31 doi:10.1186/1471-2164-7-31 |
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