Research article
Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebrates
1 Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520, USA
2 Department of Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA
BMC Genomics 2006, 7:248 doi:10.1186/1471-2164-7-248
Published: 4 October 2006Additional files
Additional File 1:
Phylogenetic relationship of PEDF to other serpins. A total of 88 serpins with 14 PEDF sequences were used to construct this bootstrap consensus tree based on 500 replicates. The numbers on nodes are bootstrap values.
Format: XLS Size: 85KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional File 2:
Intron-Exon junction sequences of the PEDF gene for human, mouse, chick, western clawed frog, zebrafish, and fugu. Intron sequences shown in lower case and exon sequences in upper case.
Format: DOC Size: 28KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 3:
List of PCR primers for PEDF RT-PCR analysis from each species.
Format: DOC Size: 26KB Download file
This file can be viewed with: Microsoft Word Viewer


