Table 1

Maximal numbers of transcription factors from each super-family in a single organism, and the organism in which the maximum is observed.

Super-family

Maximal # TFs

Kingdom

organism

P

S

O

H

# sequences


1

lambda repressor-like DNA-binding domains

77

A,B,E

Photorhabdus luminescens

3

1

2

1

64

2

C-terminal effector domain

88

A,B,E

Streptomyces avermitilis

-

-

-

-

-

3

srf-like

122

E

Arabidopsis thaliana

-

-

-

-

-

4

helix-loop-helix DNA-binding domain

186

E

Arabidopsis thaliana

2

1

1

2

128

5

DNA-binding domain

194

B,E

Oryza sativa

-

-

-

-

-

6

Zn2/Cys6 DNA-binding domain

246

E

Fusarium graminearum

3

13

3

1

1,248

7

winged helix DNA-binding domain

299

A,B,E

Bordetella bronchiseptica

6

1

1

1

2,048

8

glucocorticoid receptor-like DNA-binding domain

376

A,B,E

C.elegans

2

9

3

2

3,456

9

homeodomain-like

417

A,B,E

Danio rerio

6

1

1

2

8.4*106

10

multi-domain C2H2 zinc fingers

1308

E

Mus musculus

6–30

1

1

1

-


The kingdom in which each super-family is observed is abbreviated as A – Archea, B – Bacteria, E – Eukaryotes. Estimates for the number of possible sequences are shown (see methods). P – number of variable positions in each half-site, S – number of possible spacing between half-sites, O – number of possible orientations, H – homo-dimers (1) or hetero-dimers (2). The number of sequences is 4P*H*O*S/2.

Itzkovitz et al. BMC Genomics 2006 7:239   doi:10.1186/1471-2164-7-239

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