A comparison of chicken and cow GO annotations from AgBase and EBI-GOA. We are currently focused on providing GO annotations for chicken and cow gene products and we collaborate with EBI-GOA to provide a combined GO gene association file for each of these species. The number of GO annotations for chicken and cow is represented here based on GO evidence code; details about the GO evidence codes can also be found on the GO Consortium homepage . (1) Unlike EBI-GOA, AgBase does not currently annotate to IEA. (2) In newly sequenced genomes, such as cow and chicken, a large proportion of gene products are not represented in the UniProtKB database (Table 1) and are not annotated by EBI-GOA. To complement the EBI-GOA annotation effort and provide breadth of coverage, we identify the expression of these 'predicted' gene products in vivo and, where possible, provide GO annotations. (3) By definition, there is no published literature for these 'predicted' proteins and they can only be GO annotated using either IEA or ISS.
McCarthy et al. BMC Genomics 2006 7:229 doi:10.1186/1471-2164-7-229