Table 7

Comparison of Campylobacter coverage bias. Kolmogorov-Smirnov comparison of the distributions of reads per bin from an unamplified sample of Campylobacter jejuni with an additional unamplified replicate library and libraries amplified with GenomiPhi, Repli-G, PEP and DOP. Bin Size refers to the number of bases comprising each individual bin into which the genome was broken for analysis; 100,000 reads were used for each analysis. Ranked bias was derived from ranked D statistics, lowest to highest.

Unamplified Control versus:

Unamplified Replicate

GenomiPhi

RepliG

PEP

DOP


Bin Size (bp)

10

Number of Bins

164149

Number of Reads

100000

D Statistic

0.001

0.034

0.029

0.122

0.392

P value

1.000

0.000

0.000

0.000

0.000

Ranked Bias (5 is lowest)

5

3

4

2

1

Bin Size (bp)

100

Number of Bins

16415

Number of Reads

100000

D Statistic

0.004

0.060

0.079

0.247

0.882

P value

0.997

0.000

0.000

0.000

0.000

Ranked Bias (5 is lowest)

5

4

3

2

1

Bin Size (bp)

1641

Number of Bins

1001

Number of Reads

100000

D Statistic

0.028

0.214

0.275

0.483

0.915

P value

0.814

0.000

0.000

0.000

0.000

Ranked Bias (5 is lowest)

5

4

3

2

1

Bin Size (bp)

16413

Number of Bins

100

Number of Reads

100000

D Statistic

0.074

0.248

0.307

0.505

0.842

P value

0.922

0.004

0.000

0.000

0.000

Ranked Bias (5 is lowest)

5

4

3

2

1


Pinard et al. BMC Genomics 2006 7:216   doi:10.1186/1471-2164-7-216

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