Figure 3.

Amino acid sequences, amino acids that affect IgE-reactivity, and T-cell epitopes of the PR-10 proteins. Amino acid sequences of the PR-10 proteins from B. pendula 'Tristis' (Tr), 'Schneverdinger Goldbirke' (Sv), and the B. pendula alleles from 'Long Trunk' (Lt). Amino acids associated with high allergenicity are marked with grey boxes and those associated with low IgE-reactivity (located within B-cell epitopes) are marked with black boxes [12, 14]. The locations of the two major T-cell activating regions are indicated above the consensus [22].