Open Access Research article

Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

Mark L Crowe1,2*†, Xue-Qing Wang3† and Joseph A Rothnagel1,2,3

1 The Australian Research Council Special Research Centre for Functional and Applied Genomics, The University of Queensland, Brisbane, Queensland 4072, Australia

2 Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia

3 School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia

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BMC Genomics 2006, 7:16 doi:10.1186/1471-2164-7-16

Published: 26 January 2006

Additional files

Additional File 1:

'Human/mouse homologous uORF pairs'. The conserved human uORFs with the corresponding mouse homolog. Identifers consist of the accession number of the parent RefSeq entry, with, where required, a subscript index to distinguish multiple uORFs from a single entry.

Format: XLS Size: 28KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional File 2:

'uORF and uPEP sequences'. DNA and predicted protein sequences for each conserved human and mouse uORF together with the accession number of their parent RefSeq entry. N.B. DNA sequences do not include the stop codon.

Format: XLS Size: 104KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data