Table 4

Kegg Biochemical pathway mappings for A. caninum and A. ceylanicum clusters

AC

Clusters per library

AE

Clusters per library

Total # of enzymes in KEGG



KEGG CATEGORY REPRESENTEDa

Clb

iL3

taL3

ssL3

Mixed

Enzc

Clb

iL3

Ad

Mixed

Enzc


1. Carbohydrate metabolism

1.1 Glycolysis / Gluconeogenesis

23

13

0

5

5

22

25

10

11

4

23

40

1.2 Citrate cycle (TCA cycle)

17

8

0

4

5

16

15

4

8

3

15

23

1.3 Pentose phosphate pathway

9

3

0

4

2

9

12

5

3

4

8

34

1.4 Pentose and glucuronate interconversions

8

3

0

3

2

9

9

5

4

0

8

53

1.5 Fructose and mannose metabolism

14

6

0

4

4

15

20

7

11

2

15

61

1.6 Galactose metabolism

10

4

0

4

2

8

12

6

5

1

12

37

1.7 Ascorbate and aldarate metabolism

7

4

0

2

1

4

5

5

0

0

4

29

1.8 Pyruvate metabolism

25

11

0

11

3

23

27

8

17

2

26

67

1.9 Glyoxylate and dicarboxylate metabolism

13

6

0

5

2

14

9

1

5

3

17

58

1.10 Propanoate metabolism

22

7

1

10

4

20

25

11

8

6

22

46

1.11 Butanoate metabolism

22

9

1

7

5

23

29

14

14

1

26

52

1.12 C5-Branched dibasic acid metabolism

4

3

0

1

0

2

2

1

0

1

1

20

1.13 Inositol metabolism

6

2

0

1

3

4

7

2

3

2

4

5

2. Energy metabolism

2.1 Oxidative phosphorylation

24

7

0

6

11

11

33

10

14

9

13

14

2.2 ATP synthesis

8

2

0

3

3

1

11

4

3

4

1

1

2.4 Carbon fixation

11

3

0

3

5

11

11

3

5

3

13

23

2.5 Reductive carboxylate cycle (CO2 fixation)

12

7

0

1

4

8

9

2

4

3

7

13

2.6 Methane metabolism

6

4

0

0

2

5

6

0

4

2

6

26

2.7 Nitrogen metabolism

11

2

0

5

4

14

12

5

5

2

15

64

2.8 Sulfur metabolism

5

1

0

1

3

9

6

3

1

2

9

30

3. Lipid metabolism

3.1 Fatty acid biosynthesis (path 1)

6

2

0

3

1

11

7

3

3

1

6

14

3.2 Fatty acid biosynthesis (path 2)

8

2

0

5

1

6

6

3

2

1

5

8

3.3 Fatty acid metabolism

14

6

1

6

1

17

21

13

7

1

16

28

3.4 Synthesis and degradation of ketone bodies

2

0

0

1

1

2

8

4

3

1

3

6

3.5 Sterol biosynthesis

4

1

1

2

0

4

4

2

2

0

9

35

3.6 Bile acid biosynthesis

11

7

1

2

1

11

11

6

4

1

10

27

3.8 Androgen and estrogen metabolism

7

5

0

2

0

9

7

4

3

0

8

26

4. Nucleotide metabolism

4.1 Purine metabolism

27

11

0

11

5

28

32

14

11

7

32

99

4.2 Pyrimidine metabolism

16

8

1

5

2

15

22

9

12

1

22

61

4.3 Nucleotide sugars metabolism

6

4

0

0

2

3

4

2

2

0

4

30

5. Amino acid metabolism

5.1 Glutamate metabolism

11

3

0

5

3

14

16

8

7

1

18

36

5.2 Alanine and aspartate metabolism

14

1

0

8

5

15

14

5

6

3

15

38

5.3 Glycine, serine and threonine metabolism

19

7

0

9

3

14

21

8

10

3

24

56

5.4 Methionine metabolism

6

1

0

4

1

9

6

5

1

0

8

24

5.5 Cysteine metabolism

8

2

0

2

4

11

7

5

2

0

9

23

5.6 Valine, leucine and isoleucine degradation

16

3

1

8

4

16

22

11

6

5

18

32

5.7 Valine, leucine and isoleucine biosynthesis

7

1

0

4

2

7

9

6

2

1

8

15

5.8 Lysine biosynthesis

11

1

0

6

4

10

9

4

3

2

8

31

5.9 Lysine degradation

19

8

0

8

3

14

19

12

6

1

17

47

5.10 Arginine and proline metabolism

18

4

0

8

6

20

22

11

7

4

20

71

5.11 Histidine metabolism

10

4

0

4

2

8

10

5

4

1

8

39

5.12 Tyrosine metabolism

18

8

0

7

3

19

19

11

5

3

19

67

5.13 Phenylalanine metabolism

13

5

0

3

5

11

14

7

6

1

12

40

5.14 Tryptophan metabolism

17

8

0

8

1

15

22

16

4

2

18

61

5.15 Phenylalanine, tyrosine and tryptophan biosynthesis

5

1

0

2

2

6

4

2

0

2

7

31

5.16 Urea cycle and metabolism of amino groups

10

1

0

5

4

14

10

2

6

2

11

35

6. Metabolism of other amino acids

6.1 beta-Alanine metabolism

14

4

1

7

2

13

11

8

1

2

10

32

6.2 Taurine and hypotaurine metabolism

1

0

0

0

1

1

2

2

0

0

3

14

6.3 Aminophosphonate metabolism

4

0

0

3

1

3

5

2

3

0

5

15

6.4 Selenoamino acid metabolism

7

0

0

4

3

12

12

6

4

2

15

22

6.5 Cyanoamino acid metabolism

2

1

0

1

0

1

7

5

1

1

6

19

6.6 D-Glutamine and D-glutamate metabolism

2

0

0

1

1

2

2

1

0

1

2

12

6.7 D-Arginine and D-ornithine metabolism

3

1

0

0

2

2

3

0

2

1

2

10

6.9 Glutathione metabolism

5

1

0

0

4

4

9

5

3

1

6

27

7. Metabolism of complex carbohydrates

7.1 Starch and sucrose metabolism

18

2

0

13

3

18

20

13

6

1

20

75

7.2 N-Glycans biosynthesis

7

4

0

1

2

7

7

2

4

1

9

27

7.3 O-Glycans biosynthesis

3

1

0

1

1

2

6

5

1

0

3

8

7.5 Aminosugars metabolism

6

3

0

2

1

6

10

5

5

0

10

39

7.8 Glycosaminoglycan degradation

1

1

0

0

0

1

1

1

0

0

1

13

7.9 Chondroitin / Heparan sulfate biosynthesis

5

3

0

1

1

4

6

2

4

0

4

18

7.10 Keratan sulfate biosynthesis

1

0

0

1

0

1

2

1

1

0

1

6

8. Metabolism og complex lipids

8.1 Glycerolipid metabolism

24

10

0

9

5

22

25

10

13

2

22

80

8.3 Inositol phosphate metabolism

8

4

0

4

0

4

8

5

2

1

3

25

8.4 Sphingophospholipid biosynthesis

1

1

0

0

0

1

2

1

1

0

2

8

8.5 Phospholipid degradation

3

2

0

0

1

3

1

1

0

0

1

11

8.6 Sphingoglycolipid metabolism

11

1

1

9

0

7

10

8

2

0

4

20

8.9 Globoside metabolism

2

1

0

1

0

2

2

1

1

0

1

12

8.11 Prostaglandin and leukotriene metabolism

8

2

0

1

5

8

7

4

3

0

6

19

9. Metabolism of cofactors and vitamins

9.2 Riboflavin metabolism

4

1

0

3

0

2

2

2

0

0

2

13

9.3 Vitamin B6 metabolism

6

4

0

1

1

3

6

4

1

1

5

23

9.4 Nicotinate and nicotinamide metabolism

11

2

0

7

2

7

15

8

7

0

7

32

9.5 Pantothenate and CoA biosynthesis

8

2

0

4

2

9

8

6

2

0

7

27

9.7 Folate biosynthesis

5

2

1

0

2

5

6

1

4

1

5

25

9.8 One carbon pool by folate

5

3

0

2

0

10

7

3

3

1

8

24

9.10 Porphyrin and chlorophyll metabolism

18

4

0

10

4

12

27

15

8

4

13

56

9.11 Ubiquinone biosynthesis

19

10

0

5

4

13

28

11

14

3

14

22

10. Biosynthesis of secondary metabolites

10.1 Terpenoid biosynthesis

0

0

0

0

0

0

2

0

2

0

4

12

10.3 Flavonoids, stilbene and lignin biosynthesis

6

3

0

1

2

7

8

5

3

0

7

39

10.4 Alkaloid biosynthesis I

5

2

0

3

0

6

3

3

0

0

5

36

10.8 Streptomycin biosynthesis

2

0

0

2

0

3

4

2

1

1

4

14

10.9 Erythromycin biosynthesis

2

0

0

2

0

3

3

2

1

0

3

6

11. Biodegradation of xenobiotics

11.4 Nitrobenzene degradation

4

1

0

3

0

5

4

2

1

1

3

17

11.9 Tetrachloroethene degradation

6

4

0

1

1

3

2

2

0

0

3

5

11.10 Styrene degradation

4

2

0

2

0

3

6

5

0

1

5

18

11.1 gamma-Hexachlorocyclohexane degradation

6

3

0

3

0

5

5

3

2

0

4

12

11.1 Fluorene degradation

3

1

0

2

0

4

2

2

0

0

2

13

11.2 Benzoate degradation via CoA ligation

22

8

1

10

3

18

25

14

10

1

18

38

11.2 Benzoate degradation via hydroxylation

7

2

0

5

0

7

5

4

1

0

5

45


aA. caninum – 839 multiple and 786 unique mappings; A. ceylanicum – 957 multiple and 840 unique mappings. b Cluster, c Enzymes

Mitreva et al. BMC Genomics 2005 6:58   doi:10.1186/1471-2164-6-58

Open Data