Spatial correlation of transcription factor gene families to UCRs in the human genome. A. Cumulative distribution of distances to the closest UCR for selected subsets of genes. Distance to the closer end of the transcript mapping (either 3' or 5'). Majority of major classes of transcription factors are closer to UCRs than random genes. B, C. Occurrence of UCRs around selected subsets of genes. This plot summarizes the distribution of distances to all UCRs on the same chromosome for each gene in the subset. There is a visible over-representation of UCRs up to 300 kb from homeobox genes, and up to 150 kb from C2H2 zinc finger genes.
Sandelin et al. BMC Genomics 2004 5:99 doi:10.1186/1471-2164-5-99