Figure 7.

Putative recombination pathway for transfer of the 2DL5-2DS35 gene block between the centromeric and telomeric motifs. An exchange between the intron 2B regions of 2DL5A (tB01) and 3DP1 (cB02) is depicted, yielding the KIR-cB02|tB01-del6 haplotype. A second exchange between the intergenic regions of 2DS35-2DS1 in KIR-cB02|tB01-del6 and 2DL3/2DS3/S5-2DP1 in the cA01 or cB01 motifs is depicted yielding the cB01 motif with resultant transfer of the 2DL5-2DS35 gene block. Supporting alignment, breakpoint, and phylogenetic analyses for this pathway are presented in Additional file 2: Figure S5.

Pyo et al. BMC Genomics 2013 14:89   doi:10.1186/1471-2164-14-89
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