Genes differentially regulated between the 5 breeds. (A) 140 Snowball Affymetrix microarrays were used to create a principal components analysis (PCA) in function of breeds (DU in red, HAM in blue, LR in green, LW in purple and PIE in yellow). Although the PCA showed again clusters in function of the compartment and the timing, no cluster specific to breed could be observed (B) 3-way ANOVA test showed a small number of genes DR in function of the breed. The table includes the number of genes DR between breeds (p < 0.01 , FC >3 or <-3) after 7 h of LPS stimulation. (C) All the genes differentially expressed in AM were grouped into a heat-map. Duplicated probesets were removed, a total of 108 different genes were plotted (p <0.01 and fold change >3 or <-3). The blue color in the heat-map represents down-regulation of the gene and the red up-regulation of the gene in function to the average expression of the probeset.
Kapetanovic et al. BMC Genomics 2013 14:581 doi:10.1186/1471-2164-14-581