In silico analysis of detected deletions by restriction ditags. A) Evaluation of the detection resolution of deleted restriction sites with a wide range of cutting frequencies. The bar plot represents the fraction of detectable deletions associated with restriction sites in the YH genome (blue) and the DGV database (red). The dark line represents the estimated sequence input for various restriction sites, assuming that the restriction ends are covered by an average of 12× paired 50-bp reads. B) The fraction of deletions that are targeted by TaqI ditags (cutting at T,CGA) across various size ranges in YH genome.
Gong et al. BMC Genomics 2013 14:51 doi:10.1186/1471-2164-14-51