Table 3

N. apis sequences that show homology to annotated and experimentally verified pathogenicity and virulence genes of microsporidia species
Product/Gene Sequence ID Function Homologous to N. ceranae Organism whose annotated sequence has top BlastP hit Reference
1) Polar Tube Protein
PTP2 NAPIS-00435 Yes N. bombycis [77]
PTP3 NAPIS-01921 Host cell invasion Yes N. bombycis [77]
PTP3 NAPIS-01922 Yes N. bombycis [77]
2) Spore Wall Protein
SWP12 NAPIS-00521 Yes N. bombycis [78]
SWP25 NAPIS-00461 Yes N. bombycis [79]
NAPIS-00514 Structural capacity & Yes N. bombycis [79]
NAPIS-01092 host cell adhesion Yes N. bombycis [79]
SWP26 NAPIS-00203 Yes N. bombycis [80]
SWP32 NAPIS-00269 Yes N. bombycis [78]
3) Endochitinase
NAPIS-02055 Spore attachment Yes E. hellem [56]
NAPIS-02138 No E. hellem [56]
4) Chitin synthase
NAPIS-01775 Spore attachment Yes E. intestinalis [53]
NAPIS-02139 & pathogenicity Yes E. hellem [56]
6) Mitogen-activated protein kinase
NAPIS-01928 Pathogenicity Regulation Yes E. intestinalis [53]
7) ATP/ADP Translocase
NAPIS-01593 Yes E. cuniculi [50]
NAPIS-01593 Energy parasitism Yes E. cuniculi [50]
NAPIS-02128 Yes E. cuniculi [50]
NAPIS-02287 Yes E. cuniculi [50]
8) Transferase
NAPIS-00457 No E. hellem [56]
NAPIS-00459 Pathogenicity Yes E. cuniculi [50]
NAPIS-00459 regulation Yes E. intestinalis [53]
NAPIS-00578 No E. hellem [56]
NAPIS-00596 Yes E. hellem [56]
9) Splicing machinery
NAPIS-00564 Yes E. intestinalis [53]
NAPIS-00654 Pathogenicity Yes E. intestinalis [53]
NAPIS-01012 regulation Yes E. hellem [56]
NAPIS-02190 Yes E. romaleae [56]
  9) Putative secretive proteins (399 proteins listed in Additional file 4: Table S1)

Chen et al.

Chen et al. BMC Genomics 2013 14:451   doi:10.1186/1471-2164-14-451

Open Data