Genes expressed at ≥2-fold (as per microarray) in each cell line, relative to each other, were analyzed using the DAVID bioinformatics tool. The graph shows an example of two biological processes (GO Terms) that have an EASE score < 0.05: “response to organic stimuli” and “regulation of transcription”. A fold-difference > 1 indicates high expression in AR-5 and < 1 indicates high expression in IVB cells. The following genes are shown in the graph: (Aldh3a1) aldehyde dehydrogenase 3A1, (Avpr1a) Arginine vasopressin receptor 1A, (Cox5B) cytochrome c oxidase subunit Vb, (MT-CYB) cytochrome b, (Dnajb5) DnaJ (Hsp40) homolog subfamily B member 5, (Dnajc3) DnaJ (Hsp40) homolog subfamily C member 3, (E2f1) E2F transcription factor 1, (Fos) FBJ osteosarcoma oncogene, (GRLF1) glucocorticoid receptor DNA binding factor 1, (Hdac6) histone deacetlyase 6, (Hsp90ab1) heat shock protein 90 kDa alpha class B member 1, (Jun) Jun proto-oncogene, (KAT5) Lysine (K) acetyltransferase 5, (Kdm1) Lysine (K)-specific demethylase 1, (kdm3a) lysine (K)-specific demethylase 3A, (MT-ND1-3) NADH-ubiquinone oxidoreductase chain 1–3, (Nr1h3) liver x receptor alpha, (Nr2f2) COUP transcription factor 2, (Nr3c2) mineralocorticoid receptor, (sgk1) serum/glucocorticoid regulated kinase 1.
Dalwadi and Uht BMC Genomics 2013 14:413 doi:10.1186/1471-2164-14-413