Dynamics of differential expression in heart and lung. The difference in transcript expression between sleeping and diurnally matched, sleep-deprived animals is a function of deprivation time. This heat map shows the difference in mean transcript levels between sleeping and sleep-deprived mice (in log space), as sleep deprivation continues. Darker shades represent increasing magnitudes of differential expression. Red and blue signify increased expression in sleep deprived and spontaneously sleeping animals respectively. All 156 probes that had sleep specific changes in both tissues are displayed. Dynamic changes in the lung are plotted alongside dynamic changes in the heart for the same probe. The direction of change and the temporal evolution of those changes in the heart and lung are similar.
Anafi et al. BMC Genomics 2013 14:362 doi:10.1186/1471-2164-14-362