Table 3

Major gene ontology biological process classifications represented by genes differentially expressed between control quarters from cows infected with S. aureus for 24 hours (SA24T0) and 72 hours (SA72T0)
Clone accession no. Gene symbol gene Fold Difference
RESPONSE TO STRESS
SA24T0 > SA72T0
CO891789 ASF1A ASF1 anti-silencing function 1 homolog A 2.53
pCXCL10* CXCL10 chemokine (C-X-C motif) ligand 10 3.28
AJ693004 CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.03
AM018876 FGA fibrinogen alpha chain 2.03
pIL1B* IL1B interleukin 1, beta 2.72
AM037229 PENK proenkephalin 2.23
BM256666 S100A8 S100 calcium binding protein A8 (calgranulin A) 2.19
BF655078 S100A12 S100 calcium binding protein A12 (calgranulin C) 2.29
AM031467 SOD2 superoxide dismutase 2, mitochondrial 2.30
CO875497 TP53BP1 tumor protein p53 binding protein 1 2.68
AM022673 XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 3.22
SA72T0 > SA24T0
CK847668 BRCA2 breast cancer 2, early onset 3.47
CELL PROLIFERATION
SA24T0 > SA72T0
AM009066 ACSL6 acyl-CoA synthetase long-chain family member 6 3.27
pCXCL10* CXCL10 chemokine (C-X-C motif) ligand 10 3.28
CO874867 CSRP2 cysteine and glycine-rich protein 2 2.26
AM018876 FGA fibrinogen alpha chain 2.03
pIL1B* IL1B interleukin 1, beta 2.72
AM024609 STIL SCL/TAL1 interrupting locus 2.69
SA72T0 > SA24T0
CK847668 BRCA2 breast cancer 2, early onset 3.47
BI680983 INHA inhibin, alpha 2.63
AJ815547 IL7 interleukin 7 3.38
CELL DEVELOPMENT
SA24T0 > SA72T0
AM009066 ACSL6 acyl-CoA synthetase long-chain family member 6 3.27
CO874867 CSRP2 cysteine and glycine-rich protein 2 2.26
BM256725 GZMH granzyme H 2.35
pIL1B* IL1B interleukin 1, beta 2.72
CO887046 LRRC4C leucine rich repeat containing 4C 2.46
AM031467 SOD2 superoxide dismutase 2, mitochondrial 2.30
CO892784 ZEB2 zinc finger E-box binding homeobox 2 2.84
SA72T0 > SA24T0
AJ817391 AFF4 AF4/FMR2 family, member 4 3.20
CK847668 BRCA2 breast cancer 2, early onset 3.47
BI680983 INHA inhibin, alpha 2.63
AJ815547 IL7 interleukin 7 3.38
IMMUNE RESPONSE
SA24T0 > SA72T0
AM011262 CTSG cathepsin G 2.09
BF706666 CD4 CD4 molecule 4.50
pCXCL10* CXCL10 chemokine (C-X-C motif) ligand 10 3.28
pFCGR3A* FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16) 3.09
AM023116 GBP4 guanylate binding protein 4 2.16
pIL1B* IL1B interleukin 1, beta 2.72
AM011258 LTF lactotransferrin 3.48
SA72T0 > SA24T0
AJ815547 IL7 interleukin 7 3.38
DEFENSE RESPONSE
SA24T0 > SA72T0
pCXCL10* CXCL10 chemokine (C-X-C motif) ligand 10 3.28
pIL1B* IL1B interleukin 1, beta 2.72
AM011258 LTF lactotransferrin 3.48
AM037229 PENK proenkephalin 2.23
BM256666 S100A8 S100 calcium binding protein A8 (calgranulin A) 2.19
BF655078 S100A12 S100 calcium binding protein A12 (calgranulin C) 2.29

A single accession number is listed for genes represented by multiple clones. Average fold differences were calculated for superoxide dismutase 2, mitochondrial and lactotransferrin, which are represented by multiple clones. * pCXCL10, pFCGR3A and pIL1B are amplicons generated specifically for the Bov20K cDNA microarray.

Jensen et al.

Jensen et al. BMC Genomics 2013 14:36   doi:10.1186/1471-2164-14-36

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