Open Access Research article

Acid shock of Listeria monocytogenes at low environmental temperatures induces prfA, epithelial cell invasion, and lethality towards Caenorhabditis elegans

Klaus Neuhaus1, Peter Satorhelyi12, Kristina Schauer3, Siegfried Scherer1 and Thilo M Fuchs1*

Author Affiliations

1 Lehrstuhl für Mikrobielle Ökologie, Department für biowissenschaftliche Grundlagen, Wissenschaftszentrum Weihenstephan, and ZIEL, Abteilung Mikrobiologie, Technische Universität München, Weihenstephaner Berg 3, Freising, 85350, Germany

2 Present Address: IVAX Drug Research Institute, Berlini u. 49, Budapest, 1045, Hungary

3 Present Address: Lehrstuhl für Hygiene und Technologie der Milch, Tiermedizinische Fakultät der Ludwig-Maximilians-Universität München, Schönleutnerstrasse 8, Oberschleißheim, D-85764, Germany

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BMC Genomics 2013, 14:285  doi:10.1186/1471-2164-14-285

Published: 27 April 2013

Additional files

Additional file 1:

Transcriptomic dynamic of L. monocytogenes upon acid shock at two different temperatures.

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Additional file 2:

List of genes from L. monocytogenes whose knockout led in all cases to attenuation in mouse infection experiments.

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Additional file 3:

List of the genes used for the qRT-PCR validation of the L. monocytogenes microarray experiments.

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Additional file 4:

List of genes significantly (p ≤ 0.05) down regulated after acid shock at both 25°C and 37°C.

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