CeRNA Networks. In a competing endogenous RNA (ceRNA) network, RNAs regulated by a single miRNA can compete with other mRNAs for that miRNA and control its effect on other targets. We identified mRNAs that had a single strong RISC footprint that contained a single highly-loaded miRNA and built ceRNA networks. Networks for miR-122-5p, miR-5102, mir-22-3p, mir-140-5p and mir-140-3p are shown.
Schug et al. BMC Genomics 2013 14:264 doi:10.1186/1471-2164-14-264