eQTL hotspots and their overlapping eQTL modules found by GFlasso. GFlasso found that many genes (x-axis) are jointly influenced by the same genetic loci (y-axis), suggesting that these eQTL hotspots perturb an overlapping set of genes. We group these eQTL hotspots into the Ribi, telomere, and retrotransposon groups according to their overlaps in the corresponding eQTL modules. For example, the first 722 genes (plotted along the x-axis) all belong to the eQTL module for II:560 kb, and many of these genes also belong to the eQTL modules derived from three other eQTL hotspots: V:350 kb, V:420 kb, and VII:50 kb.
Curtis et al. BMC Genomics 2013 14:196 doi:10.1186/1471-2164-14-196