Table 1

Drug selection for single stuck-at faults

Net

s-a

Faulty PO

Best PO

Drug Vector

Score


1

1

1111111

0000000

010000

85

2

1

1111111

0000000

100000

85

3

1

1111111

0000000

001000

85

4

1

1111111

0000000

010000

85

5

1

1111111

0000000

000110

84

6

1

0000111

0000000

000110

84

7

1

0000111

0000111

000000

56

8

1

1111111

0000000

000010

85

9

1

0000111

0000000

000010

85

10

1

0000111

0000111

000000

56

11

1

0000111

0000111

000000

56

12

1

0000111

0000111

000000

56

16

1

0111110

0000000

000100

85

17

1

0111110

0000000

000100

85

18

1

0111110

0111110

000000

36

19

0

0000001

0000001

000000

76

20

0

0000110

0000000

000001

85

21

1

0000110

0000000

000001

85

22

1

0000110

0000000

000001

85

23

1

0000110

0000110

000000

66

24

0

0000110

0000110

000000

66


Each row in the table corresponds to a single fault, located by the net number and the type of fault (stuck-at-1 or stuck-at-0). The primary output [FOS - JUN,SP1,SRF - ELK1,SRF - ELK4,BCL2,BCL2L1,CCND1] shown is the expression value where 1 means the gene is expressed, while 0 means the gene is not expressed. The drug vector [lapatinib,AG825,AG1024,U0126,LY249002,Temsirolimus] indicates the drug selection where 1 means the drug is selected, while 0 means the drug is not used.

Lin and Khatri BMC Genomics 2012 13(Suppl 6):S5   doi:10.1186/1471-2164-13-S6-S5

Open Data