Effect of saturation. Effect of instrument response κ in the presence of saturation on (a) missing value rates, (b) quantification accuracy, (c) differential expression results, and (d) classification error rates. As κ increases, all performance indices at first improve and then deteriorate (except for the peptide missing value rate, which levels off).
Sun et al. BMC Genomics 2012 13(Suppl 6):S2 doi:10.1186/1471-2164-13-S6-S2