Effect of sample size. Effect of sample size M on (a) differential expression results, and (b) classification error rates. All results generally improve as M increases. In (b) the classification error of the original protein sample (dashed lines) is plotted side by side with that of the observed protein data (solid lines), illustrating the substantial loss in accuracy introduced by the MS analysis pipeline.
Sun et al. BMC Genomics 2012 13(Suppl 6):S2 doi:10.1186/1471-2164-13-S6-S2