Effect of MS2 replication. Effect of MS2 replication on (a) missing value rates, (b) quantification accuracy, (c) differential expression results, and (d) classification errors. It can be seen that replicate analysis can significantly boost peptide and protein identification rates, quantification and classification results even only a few replicates are made available.
Sun et al. BMC Genomics 2012 13(Suppl 6):S2 doi:10.1186/1471-2164-13-S6-S2