Table 6

TP53 overlapping cluster membership

Pathway Name, (enrichment p-value)

HPD similarity grouping

de novo Gene Membership

de novo Gene Ontology

de novo Protein Interactants


G1 to S cell cycle control (p = 7.30 × 10-3)

G2_PATHWAY (p = 2.58 × 10-3)



Class I PI3K signaling events mediated by AKT (p = 0.14)

DNA damage response (p = 7.20 × 10-3)


MAPK signaling pathway (p = 2.88 × 10-2)


Glioma (p = 6.70 × 10-3)

Non-small cell lung cancer (p = 5.80 × 10-3)

Melanoma (p = 7.63 × 10-3)

Endometrial Cancer (p = 5.59 × 10-3)


Note: p-values are derived from one-tail Fisher's Exact test, before multiple test correction. Dividers and matching symbols indicate pathways groups within a consolidation method.

Doderer et al. BMC Genomics 2012 13(Suppl 6):S18   doi:10.1186/1471-2164-13-S6-S18

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