Table 5

Tamoxifen relevant proteins and their directionality

Drug

Protein

RpScore

Association

Direction


Tamoxifen

AKT1_HUMAN

82.99

1.77

1

Tamoxifen

BRCA2_HUMAN

21.14

3.29

1

Tamoxifen

CADH1_HUMAN

17.57

0.95

1

Tamoxifen

CDK2_HUMAN

2.94

2.12

1

Tamoxifen

E2F1_HUMAN

2.95

1.59

1

Tamoxifen

ERBB2_HUMAN

2.07

3.19

1

Tamoxifen

ESR1_HUMAN

72.39

5.11

-1

Tamoxifen

IRS1_HUMAN

2.51

1.29

-1

Tamoxifen

JUN_HUMAN

2.91

1.51

1

Tamoxifen

MYC_HUMAN

3.49

2.5

1

Tamoxifen

NCOA3_HUMAN

2.61

3.01

-1

Tamoxifen

NCOR1_HUMAN

2.81

4.05

1

Tamoxifen

P53_HUMAN

169.82

0.8

-1

Tamoxifen

P85A_HUMAN

2.92

1.57

1

Tamoxifen

PTEN_HUMAN

3.98

0.98

1

Plicamycin

MYC_HUMAN

3.49

4.16

-1

Plicamycin

SP1_HUMAN

3.32

6.24

-1


1 represents that the drug up regulates the protein while -1 represents down regulation

Huang et al. BMC Genomics 2012 13(Suppl 6):S17   doi:10.1186/1471-2164-13-S6-S17

Open Data