Figure 5.

Tracking groups in hierarchical clustering. The top panel shows the initial clustering dendrogram of methylation in gene promoters among four groups of AML patients (feature threshold criteria: average rpm > 0, CV > 3). Membership in the two largest clusters is then tracked in subsequent dendrograms by blue (left cluster) and red (right cluster) sample labels. Black labels indicate samples not present in the two largest clusters. Middle panel, clustering dendrogram of CpG island methylation (feature threshold criteria: average rpm > 0, CV > 3). Bottom panel, clustering dendrogram of methylation in CpG island shores (feature threshold criteria: average rpm > 0, CV > 3).

Rodriguez et al. BMC Genomics 2012 13(Suppl 6):S14   doi:10.1186/1471-2164-13-S6-S14