Table 6

Performance for optimizing the combination of five drugs in the presence of noise.

Noise level

Search type

Performance metric

Gur Game (simultaneous)

Gur Game (sequential)

Previous search algorithm [11](α = 1)

ARU algorithm (proposed) (α = 1)


f5a(x)

(2%)

A

success rate unique comb.

8%

9%

100%

100%

2.1

4.4

139.3

122.5

B

success rate iterations

9%

11%

100%

100%

2.1

6.0

172.4

154.9


(5%)

A

success rate unique comb.

9%

11%

100%

100%

3.9

7.9

142.1

129.1

B

success rate iterations

9%

12%

100%

100%

108.3

38.6

177.1

155.6


(8%)

A

success rate unique comb.

10%

13%

100%

100%

7.1

20.2

144.5

131.4

B

success rate iterations

9%

13%

100%

100%

191.4

70.8

182.3

156.5


f5b(x)

(2%)

A

success rate unique comb.

89%

55%

100%

100%

917.9

1026.3

407.1

343.9

B

success rate iterations

90%

55%

100%

100%

999.8

1325.1

516.5

444.3


(5%)

A

success rate unique comb.

90%

59%

97%

98%

932.8

1002.7

507.7

463.6

B

success rate iterations

90%

56%

99%

99%

1004.7

1332.7

656.9

562.4


(8%)

A

success rate unique comb.

91%

59%

97%

98%

959.5

971.2

578.8

534.8

B

success rate iterations

90%

56%

99%

99%

1015.2

1341.0

735.0

668.6


Kim and Yoon BMC Genomics 2012 13(Suppl 6):S12   doi:10.1186/1471-2164-13-S6-S12

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