Table 4

Performance for optimizing the combination of three drugs in the presence of noise.

Noise level

Search type

Performance metric

Gur Game (simultaneous)

Gur Game (sequential)

Previous search algorithm [11](α = 1)

ARU algorithm (proposed) (α = 1)


f3a(x)

(2%)

A

success rate unique comb.

1%

3%

99%

100%

2.4

7.3

110.6

77.3

B

success rate iterations

1%

3%

99%

100%

2.8

10.9

201.1

139.6


(5%)

A

success rate unique comb.

1%

3%

99%

100%

2.4

7.4

111.7

78.4

B

success rate iterations

1%

3%

99%

100%

2.5

10.1

201.6

144.0


(8%)

A

success rate unique comb.

1%

3%

99%

100%

2.5

7.7

113.3

80.5

B

success rate iterations

1%

3%

99%

100%

2.3

9.4

210.9

151.7


f3b(x)

(2%)

A

success rate unique comb.

86%

69%

99%

99%

224.3

201.6

110.8

93.3

B

success rate iterations

83%

59%

99%

99%

367.1

419.1

211.5

205.3


(5%)

A

success rate unique comb.

89%

72%

99%

99%

222.3

201.6

116.6

106.2

B

success rate iterations

83%

59%

98%

98%

359.3

439.9

225.5

222.9


(8%)

A

success rate unique comb.

90%

74%

97%

98%

225.9

200.9

126.4

114.3

B

success rate iterations

82%

60%

97%

98%

359.4

431.3

249.1

246.8


Kim and Yoon BMC Genomics 2012 13(Suppl 6):S12   doi:10.1186/1471-2164-13-S6-S12

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