Table 1

Performance for optimizing the combination of two drugs.

Gur Game (simultaneous)

Gur Game (sequential)

Previous search algorithm [11](α = 1)

ARU algorithm (proposed) (α = 1)


success rate

unique comb.

success rate

unique comb.

success rate

unique comb.

success rate

unique comb.


f2a(x) : HIV INHIBITION

(M = 80)

97%

13.2

95%

17.2

100%

13.4

100%

12.1

f2b(x) : DEJONG (2ND)

(M = 441)

9%

3.6

10%

4.5

99%

56.2

99%

46.2

f2c(x) : CANCER INHIBITION

(M = 100)

58%

11.3

53%

13.0

98%

13.2

98%

12.4

f2d(x): BACTERIA INHIBITION

(M = 81)

96%

5.9

91%

6.8

100%

4.8

100%

4.5


Kim and Yoon BMC Genomics 2012 13(Suppl 6):S12   doi:10.1186/1471-2164-13-S6-S12

Open Data