Comparison of Λ. a) The coefficient of variation of BR1 (calculated from Case I Figure 3)and BR1R2 complexes (calculated from Case II Figure 3) is compared. The variability of the system seems to be invariant in the presence of Type II. b) Concentration dependency of Λ as a function of R2. c) Same as plot "a", however, direct interaction of BMP and Type II is allowed as in Case III, Figure 3. It's clear that the stochasticity of the system does not change over the range of values tested. d) Summary of BR1R2 formation and its impact on signaling noise.
Karim et al. BMC Genomics 2012 13(Suppl 6):S10 doi:10.1186/1471-2164-13-S6-S10