Additional file 3.
Supplementary figure 3.png Grid optimization of the predictive power of the classifier (populated groups): F-score. Grid optimization of the predictive power of the classifier when only the groups with a reasonable number of reported disease-associated mutations are considered. We exhaustively tested soft-margin (C) and γ. The average f-score across the entire set of k-folds was chosen as the scoring function for the optimization. The optimal values used during the analyses were C = 8 and γ = 10–4.
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Izarzugaza et al. BMC Genomics 2012 13(Suppl 4):S3 doi:10.1186/1471-2164-13-S4-S3