Separation of classes In most classification problems the two classes are overlapping. By moving the cut off position the amount of the overlap of the classes can be adjusted. FN and FP are misclassified cases. The prediction methods aim at optimizing the cut off and thereby adjusting the numbers in the contingency table.
Vihinen BMC Genomics 2012 13(Suppl 4):S2 doi:10.1186/1471-2164-13-S4-S2