Performance of imiRTP by integrating multiple predictors. It's clear that directly combine results of single online predictors, we can't expect imiRTP achieves higher true positive than the best single method. At the other side, we will get the lowest additional prediction, which contains fewest true negatives. Here, with the multi-method cutoff, imiRTP can achieve the best balance between true positive and additional prediction.
Ding et al. BMC Genomics 2012 13(Suppl 3):S3 doi:10.1186/1471-2164-13-S3-S3