Figure 2.

Accuracy comparison for four different SNV detection methods on the NA12878 hard merged alignments. The tradeoff between sensitivity and specificity is controlled in the Bayesian methods (SNVQ, SOAPsnp, and Maq) by varying the minimum probability of having a genotype different than the reference, while in PMA it is controlled by varying the maximum p-value required to reject the null hypothesis of absence of variants.

Duitama et al. BMC Genomics 2012 13(Suppl 2):S6   doi:10.1186/1471-2164-13-S2-S6