Table 2

A summary of results for system noise with standard deviation 1 and observation noise with standard deviation 0.1

(a)


Equally spaced

Unequally spaced


# of time points

50

25

50

25


# TP

# FP

PRE

# TP

# FP

PRE

# TP

# FP

PRE

# TP

# FP

PRE

Proposed

295.9

41.7

0.88

238.4

71.6

0.77

262.4

42.1

0.86

110.7

37.2

0.75

ENet1

246.3

119.7

0.67

109.2

67

0.62

84.7

140.6

0.38

20.3

70.4

0.22

ENet2

277.9

130.9

0.68

212.8

130

0.62

169.7

241.5

0.41

65.5

132.5

0.33

G1DBN1

223.7

48

0.82

99.9

46.2

0.68

65.1

83.1

0.44

19.3

72.7

0.21

G1DBN2

268.8

83.4

0.76

188.1

64.5

0.74

134.8

104.4

0.56

46.7

85.7

0.35


(b)


Equally spaced

Unequally spaced


# of time points

50

25

50

25


# TP

# FP

PRE

# TP

# FP

PRE

# TP

# FP

PRE

# TP

# FP

PRE

Proposed

39.8

13.2

0.75

23.4

20.8

0.53

31.2

16.5

0.65

5.5

15.9

0.26

ENet1

38.5

153.1

0.2

18.6

113

0.14

12.3

186.6

0.06

3.7

85

0.04

ENet2

-

-

-

-

-

-

-

-

-

-

-

-

G1DBN1

35.6

88.9

0.29

16.8

91.9

0.15

10.3

121.9

0.08

2.4

87.8

0.03

G1DBN2

-

-

-

-

-

-

-

-

-

-

-

-


(a) The number of true positives (# TP) and false positives (# FP) of estimated regulations in two network model by the proposed approach, ENet1, ENet2, G1DBN1, and G1DBN2 for equally and unequally spaced time series data. PRE denotes the precision of the results. Regulations in two networks are 305 in total. (b) The number of true positives (# TP) and false positives (# FP) of changes on regulations between two network models estimated by the proposed approach, ENet1, ENet2, G1DBN1, and G1DBN2 for equally and unequally spaced time series data. Since no changes are estimated by ENet2 and G1DBN2, their results are indicated by '-'. The regulations changed in two networks are in total 47.

Kojima et al. BMC Genomics 2012 13(Suppl 1):S6   doi:10.1186/1471-2164-13-S1-S6

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