Table 3

Inconsistent expression ratios of 5p arm miRNA to 3p arm miRNA between tissues

Pre-miRNA

Location

N5p

N3p

Ratio_N53p

T5p

T3p

Ratio_T53p

Fold change


hsa-mir-17

MA:14-36;mi:51-72

4,767

2,266

2.1037

6,656

425

15.6612

7.44

hsa-mir-511-1

5p:16-36

39

903

0.0432

53

147

0.3605

8.35

hsa-mir-511-2

5p:16-36

39

903

0.0432

53

147

0.3605

8.35

hsa-mir-423

5p:17-39;3p:53-75

20,920

8,945

2.3387

1,708

6,266

0.2726

8.58

hsa-mir-30c-1

MA:17-39;mi:56-77

67,040

50

1,340.8000

8,685

64

135.7031

9.88

hsa-mir-135b

MA:16-38;mi:55-76

360

19

18.9474

171

99

1.7273

10.97

hsa-mir-376a-1

mi:7-28;MA:44-64

1,646

14

117.5714

569

54

10.5370

11.16

hsa-mir-376a-2

3p:50-70

428

14

30.5714

99

54

1.8333

16.68

hsa-mir-335

MA:16-38;mi:52-73

3,509

110

31.9000

418

264

1.5833

20.15

hsa-mir-30b

MA:17-38;mi:55-76

50,988

51

999.7647

3,931

89

44.1685

22.64


Location column denotes the relative locations of mature miRNAs within their precursors. N5p, T5p individually denote the expression levels of 5p arm miRNA (determined by summing the read counts of all its isomiRs) in normal and tumor tissue; while, N3p, T3p denote the corresponding information of 3p arm miRNA. The N5p and N3p values shown in this study are normalized.

Li et al. BMC Genomics 2012 13(Suppl 1):S13   doi:10.1186/1471-2164-13-S1-S13

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