Table 3

TFs that prefer regulation of h2h genes

TF

#h2h1

e-score2

f-score3

#PPI4

%PPI5

#gene6

%h2h7


STP2

7

0.375

4.358

3

42.9

235

6.0

RME1

6

0.240

3.437

0

0.0

156

7.7

PDR3

12

0.288

2.931

2

16.7

446

5.4

SFP1

22

0.335

2.452

0

0.0

432

10.2

GCN4

195

0.269

2.250

1

0.5

2,058

19.0

SFP1

42

0.335

2.225

0

0.0

886

9.5

RPN4

41

0.248

2.130

0

0.0

169

48.5

FHL1

57

0.273

2.101

0

0.0

1,120

10.2

MET4

757

0.330

2.034

26

3.4

19,090

7.9


1 Number of h2h gene pairs both bound/regulated by the TF. 2 Average co-expression of the h2h gene pairs. 3 Average functional similarity of the h2h gene pairs. 4 Number of the h2h gene pairs with interactions. 5 Ratio of the h2h gene pairs with interactions. 6 Number of genes bound/regulated by the TF with evidence. 7 Ratio of genes bound/regulated by the TF that are h2h genes.

Chang et al. BMC Genomics 2012 13(Suppl 1):S11   doi:10.1186/1471-2164-13-S1-S11

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