Table 1

Overall Most Highly Expressed Genes in the SAE of Healthy Nonsmokers1

Gene symbol

Gene title

Expression level in SAE (RPKM)2


SCGB1A1

secretoglobin, family 1A, member 1 (uteroglobin)

38675

SCGB3A1

secretoglobin, family 3A, member 1

7838

SLPI

secretory leukocyte peptidase inhibitor

1602

C20orf114

chromosome 20 open reading frame 114

1484

TPPP3

tubulin polymerization-promoting protein family member 3

1302

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

947

TMEM190

transmembrane protein 190

945

GSTP1

glutathione S-transferase pi 1

859

WFDC2

WAP four-disulfide core domain 2

840

C20orf85

chromosome 20 open reading frame 85

738

TSPAN1

tetraspanin 1

664

C9orf24

chromosome 9 open reading frame 24

629

NEAT1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

565

S100A11

S100 calcium binding protein A11

540

KRT19

keratin 19

493

MALAT1

metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)

461

ODF3B

outer dense fiber of sperm tails 3B

392

CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

374

FOXJ1

forkhead box J1

363

LCN2

lipocalin 2

359

PIGR

polymeric immunoglobulin receptor

351

MS4A8B

membrane-spanning 4-domains, subfamily A, member 8B

348

ALDH3B1

aldehyde dehydrogenase 3 family, member B1

342

MSMB

microseminoprotein, beta-

333

RSPH1

radial spoke head 1 homolog (Chlamydomonas)

318

CLDN4

claudin 4

308

AQP3

aquaporin 3 (Gill blood group)

308

C9orf117

chromosome 9 open reading frame 117

302

IGFBP2

insulin-like growth factor binding protein 2, 36 kDa

297

ANXA2P2

annexin A2 pseudogene 2

292


1 Listed are the top 30 most highly expressed SAE enriched genes.

2 Median for n = 5 healthy nonsmokers. PARTEK implementation of Bowtie algorithm with parameters as described in Material and Methods.

Hackett et al. BMC Genomics 2012 13:82   doi:10.1186/1471-2164-13-82

Open Data