Additional File 3.

Supporting Figure S3: Predictive performance and pairwise correlation of amino acid-associated weights are higher for serum IgG than for monoclonal antibodies. (A) Predictive performance values (Q2) were calculated for monoclonal (mAb) and serum IgG antibody (Sera IgG) binding profiles. (B) Shown is the pairwise correlation (r) of the corresponding AAWS <a onClick="popup('http://www.biomedcentral.com/1471-2164/13/79/mathml/M30','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2164/13/79/mathml/M30">View MathML</a>. In both (A) and (B) mAb signifies antibody binding profiles from 13 monoclonal antibodies and Sera IgG binding profiles from 58 BALB/c mice sera. Differences in predictive performance (Q2) and pairwise correlation (r) of AAWS between monoclonal and serum IgG antibodies are significant (p < 0.001). Antibody binding profiles were measured with the standard peptide library of 255 14-mers. Corresponding AAWS (<a onClick="popup('http://www.biomedcentral.com/1471-2164/13/79/mathml/M30','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2164/13/79/mathml/M30">View MathML</a>) were determined with Equation 1.

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Greiff et al. BMC Genomics 2012 13:79   doi:10.1186/1471-2164-13-79