Cluster analysis of FOXP3-dependent expressional changes in resting and PMA/ionomycin–stimulated J-FOXP3 and J-GFP cells. Color coding represents z-scores of normalized expression signal intensities. Black boxes indicate the presence of at least one FOXP3 ChIP region within the transcript’s promoter region in the range of -10 kb to +2.45 kb around the TSS as determined by ChIP-on-chip analysis and GPAT annotation of resting and stimulated J-FOXP3 cells.
Jeron et al. BMC Genomics 2012 13:705 doi:10.1186/1471-2164-13-705