Taxonomic variation in genes assigned to KOs associated with glycolysis in human gut microbiomes from 13 healthy individuals. The pathway module M00002_1 comprising 6 steps shows glycolysis (core module involving 3-carbon compounds), and K number in each box indicates KO assigned for every individual reaction. Because K00134 and K00150 have the relationship of “Or” as explained in Figure 2, if the gene from human gut microbiomes is assigned to either K00134 or K00150, the reaction at the 2nd step can be executed. Pie charts show taxonomic breakdown of the genes assigned to KOs in all 6 steps. Numbers in parentheses indicate the number of the genes assigned to KO in each reaction step.
Takami et al. BMC Genomics 2012 13:699 doi:10.1186/1471-2164-13-699