Table 2 |
|||||
| Classification with CBS of TF binding motifs that are enriched in promoters of 48 class III genes reported to be relevant for wing imaginal disc regeneration51 | |||||
| Rank | Model | Source | Genes | Genome | P Value |
| 1 | AP1 | BLS | 14 | 838 | 0 |
| 2 | TBP | JASPAR | 10 | 573 | 2.26e-12 |
| 3 | V$TATA_01 | TRANSFAC | 10 | 573 | 1.55e-11 |
| 4 | CrebA | BLS | 10 | 1007 | 1.21e-06 |
| 5 | V$CDXA_01 | TRANSFAC | 30 | 5884 | 2.97e-06 |
| 6 | V$AP1_C | TRANSFAC | 8 | 746 | 5.41e-06 |
| 7 | V$AP1_Q2 | TRANSFAC | 8 | 704 | 7.93e-06 |
| 8 | V$ELF1_Q6 | TRANSFAC | 5 | 358 | 1.46e-05 |
| 9 | V$AP1_Q6 | TRANSFAC | 8 | 811 | 1.93e-05 |
| 10 | I$GRH_01 | TRANSFAC | 13 | 1721 | 2.06e-05 |
| 11 | TATA | BLS | 5 | 377 | 2.28e-05 |
| 12 | V$USF_Q2 | TRANSFAC | 5 | 410 | 3.70e-05 |
| 13 | V$AP1_Q4 | TRANSFAC | 6 | 551 | 4.96e-05 |
| 14 | V$CDXA_02 | TRANSFAC | 32 | 7214 | 6.85e-05 |
| 15 | V$STAT5A_04 | TRANSFAC | 29 | 6281 | 8.48e-05 |
| 16 | GATA2 | JASPAR | 33 | 7698 | 1.10e-04 |
| 17 | V$PAX2_02 | TRANSFAC | 29 | 6446 | 1.61e-04 |
| 18 | V$TBP_Q6 | TRANSFAC | 24 | 5032 | 2.53e-04 |
| 19 | ct | JASPAR | 19 | 3562 | 3.92e-04 |
| 20 | V$GATA1_05 | TRANSFAC | 7 | 803 | 4.51e-04 |
For each predictive model, the following attributes are shown: rank, name of the model, regulatory catalog, gene promoters in which such a motif is detected, number of gene promoters in the whole genome in which the same motif is identified under the same constraints, and P value. Here we show only the best 20 motifs reported by CBS (see http://compfly.bio.ub.es/CBS/listTF_CBS.php webcite for further details on each predictive model).
Blanco and Corominas BMC Genomics 2012 13:688 doi:10.1186/1471-2164-13-688