Additional file 1.

Supplemental Methods. A PDF file including: data preprocessing procedures; method of moment estimation in the beta distribution; parameter choice for the Dirichlet prior; derivation of the EM algorithm for iASeq; Bayesian Information Criterion for choosing K; data generation procedure in simulation studies; single dataset based EM analysis.

Format: PDF Size: 77KB Download file

This file can be viewed with: Adobe Acrobat Reader

Wei et al. BMC Genomics 2012 13:681   doi:10.1186/1471-2164-13-681