Figure 6.

The ROC curves with chrX-npa SNPs as gold standard in the GM12878 analysis. We plot the number of non-pseudoautosomal region X chromosome SNPs, denoted by TPd(q), among the top q ranked SNPs in dataset d as a function of the rank cutoff q for each method. (a)-(g) Results in 7 representative datasets. (h) In each dataset, we computed the area under the ROC curve (AUC) using the 2000 top ranked SNPs for each method. dAUC, the proportion of improvement of AUC brought by iASeq over the best AUC from the single-dataset based methods, was computed for each dataset. The distribution of dAUC in all 40 datasets is shown.

Wei et al. BMC Genomics 2012 13:681   doi:10.1186/1471-2164-13-681
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