Figure 5.

Correlation patterns of allele-specificity among different TFs and HMs in GM12878 cells discovered by iASeq. (a) The BIC values for different class number K. The BIC achieves the minimum at K=2. (b) The estimated V and W when K=2. Each row corresponds to a class. Each column represents a dataset. The color in the cell (k,d) represents the SR or SN probability in class k and dataset d. From white to dark, the probability increases from 0 to 1. The bar plot and the numbers shown under Πare the estimated number of SNPs in each class (i.e., <a onClick="popup('http://www.biomedcentral.com/1471-2164/13/681/mathml/M39','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2164/13/681/mathml/M39">View MathML</a> the total number of SNPs). The bar plot and the numbers shown under aiare the number of SNPs identified for the corresponding class using the posterior probability Pr(ai=k|Xi,Ni,Π,V,W)>0.9 as cutoff. (c) A closer look at V and W in a number of representative datasets. The barplots show the estimated SR and SN probabilities vkdand wkdin a number of selected datasets. Left: the skewing probabilities in class 1. Right: the skewing probabilities in class 2. The height of each bar represents the SR or SN probability.

Wei et al. BMC Genomics 2012 13:681   doi:10.1186/1471-2164-13-681
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