Open Access Highly Accessed Research article

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Combiz Khozoie1, Michael G Borland14, Bokai Zhu1, Songjoon Baek2, Sam John25, Gordon L Hager2, Yatrik M Shah36, Frank J Gonzalez3 and Jeffrey M Peters1*

Author Affiliations

1 Department of Veterinary and Biomedical Sciences and The Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA, 16802, USA

2 Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD, 20892, USA

3 Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, 20892, USA

4 Present address: Department of Chemistry and Biochemistry, Bloomsburg University of Pennsylvania, Bloomsburg, PA, USA

5 Present address: Genome Sciences, University of Washington, Seattle, WA, USA

6 Present address: Department of Physiology, University of Michigan, Ann Arbor, MI, USA

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BMC Genomics 2012, 13:665  doi:10.1186/1471-2164-13-665

Published: 24 November 2012

Additional files

Additional file 1:

Table S2. 612 PPARβ/δ-dependent genes sorted by response type.

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Additional file 2:

Table S3. 203 direct PPARβ/δ target genes sorted by response type.

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Additional file 3:

Table S4. 130 genes modulated by ligand activation of PPARβ/δ in mouse primary keratinocytes.

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Additional file 4:

Table S5. 103 PPARβ/δ-dependent genes common between Khozoie et al. and Adhikary et al.

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Additional file 5:

Table S1. Primers used for the study.

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