Table 3

Differentially regulated genes in eight deletions
Systematic ID Gene name Description of gene products 2C 1C W4C S4C Gene ontology
ash2Δ SPAC3F10.17Δ SPBC2A9.02Δ SPAC27D7.08cΔ sgf73Δ meu29Δ sec65Δ pab1Δ
SPAC14C4.09 agn1+ glucan endo-1,3-alpha-glucosidase 2.7 2.0 2.4 1.9 2.6 1.9 2.9 3.1 cell septum edging catabolic process
SPAC6G10.12c ace2+ transcription factor 4.1 3.8 1.3 1.4 2.4 1.6 3.9 3.4 cytokinetic cell separation
SPAC821.09 eng1+ endo-1,3-beta-glucanase 5.7 4.1 1.5 1.1 3.1 4.2 6.3 5.9 primary cell septum disassembly
SPBC83.18c fic1+ C2 domain protein 1.8 1.6 1.3 1.3 2.3 1.9 1.3 1.3 cell cycle cytokinesis
SPCC320.13c ark1+ aurora-B kinase 1.4 1.4 1.2 1.5 2.7 2.3 1.5 1.3 cell cycle cytokinesis
SPAC17H9.19c cdt2+ WD repeat protein 2.6 1.4 3.3 1.6 2.5 1.2 2.2 3.0 DNA replication checkpoint
SPAC1F7.05 cdc22+ ribonucleoside reductase large subunit 2.7 2.3 2.1 1.6 3.3 2.3 2.5 2.8 regulation of DNA-dependent DNA replication
SPAC27E2.10c rfc3+ DNA replication factor C complex subunit 1.7 1.2 1.1 1.1 1.6 2.1 1.3 1.3 DNA-dependent DNA replication
SPAC3G6.06c rad2+ FEN-1 endonuclease 0.98 1.8 1.6 1.6 2.1 2.5 1.7 1.7 DNA replication, removal of RNA primer
SPAC821.08c slp1+ sleepy homolog 2.6 2.2 1.2 1.2 3.6 2.0 2.5 2.2 DNA replication checkpoint
SPBC1105.04c abp1+ CENP-B homolog 0.64 0.69 0.43 0.40 0.41 0.46 0.57 0.52 DNA-dependent DNA replication initiation
SPBC12D12.02c cdm1+ DNA polymerase delta subunit 1.9 2.2 1.5 1.9 1.9 1.3 2.8 3.1 DNA strand elongation involved in DNA replication
SPBC14C8.07c cdc18+ MCM loader 1.9 1.4 1.4 1.0 2.3 1.2 2.0 1.9 DNA replication checkpoint
SPBC1861.02 abp2+ ARS binding protein 1.5 1.2 0.28 0.50 0.31 0.70 0.91 0.80 DNA-dependent DNA replication initiation
SPBC428.18 cdt1+ replication licensing factor 3.0 2.8 2.3 1.7 2.2 2.2 3.5 3.3 DNA replication checkpoint
SPBC660.14 mik1+ mitotic inhibitor kinase 2.5 3.2 1.5 1.5 3.4 1.7 2.3 2.4 DNA replication checkpoint
SPCC1672.02c sap1+ switch-activating protein 1.2 0.75 1.6 1.0 2.3 1.2 1.4 1.4 replication fork arrest at rDNA repeats
SPCC23B6.05c ssb3+ DNA replication factor A subunit 2.1 1.8 1.1 1.6 1.3 1.4 1.2 1.3 DNA-dependent DNA replication
SPCC970.10c brl2+ ubiquitin-protein ligase E3 2.6 1.3 1.1 0.89 1.1 1.2 1.1 1.1 DNA replication-independent nucleosome assembly

Differentially regulated genes in the deletions comparing to WT were analyzed using an Affymetrix microarray. Genes relevant to DNA replication and cytokinesis are listed. The number represents the ratio of mRNA level in the deletion relative to that in WT.

Pan et al.

Pan et al. BMC Genomics 2012 13:662   doi:10.1186/1471-2164-13-662

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